A protein interaction network diagrams what interactions occur with a singular protein. This diagraming of interactions creates a web like structure that depicts the many different interactions that occur. Such structures help clarify specific functions of proteins and possible avenues of future research.
Interaction Network for ALK
Interaction networks can be built through many different programs such as STRING, which uses data from prior experiments to compile an accurate representation of the interactions that occur with ALK.
While ALK is found mostly in neurons, its function is still largely unknown. However, the interaction network indicates a strong indication that it has an immune function. All red highlighted proteins are proteins that have known immunological properties.
Discussion
It is clear from ALK's interaction network red region that it plays a role in immune function. However, the immune related proteins within the network have many conflicting functions making it unclear what the exact role of the protein is.
Finally, the interaction network for ALK was very similar to that of the mouse, making it an ideal model organism.